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All systems are subject to aging, even machines and software systems. Besides cancer, understanding and controlling the aging process is a central problem of applied biology. Aging means the accumulation of changes in a system, organism or object over time. For organic lifeforms, the problems of aging are senescence (the general deterioration of the body with increasing age). It is still unclear why senescence — the general deterioration of vitality and resistance to adversity with advancing age — occurs and how it works. Reasons may be:

  • normal wear and tear damage, damage that naturally and inevitably occurs in daily life
  • accumulation of waste products that interfere with metabolism
  • accumulation of mutations which violates the genetic integrity and gradually damage the genetic code
  • suppression of mechanisms that prevent further regeneration (e.g. by shortened telomeres)


  • Wikipedia link for Aging
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