Gene Regulatory Network

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A gene regulatory network or genetic regulatory network (GRN) is a number of genes or DNA segments in a cell which interact with each other (indirectly through their RNA and protein expression products) and with other substances in the cell, thereby governing the rates at which genes in the network are transcribed into RNA. GRNs orchestrate dynamically the level of expression for each gene in the genome by controlling if and how strong that gene will be transcribed into RNA. They also control the development of the animal body plan and the formation of tissues and organs.

Random boolean networks are a simple model of GRNs.

Links

  • Wikipedia Link for GRN
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